Takeaway: Being a ward of the state was so much easier for PFE.

Replay  | Vaccine Politics & PFE's Franchises - replay pfe

Today, we presented our view that PFE is probably going to have a tough time hitting that $13.5B guide for Comirnaty. Maybe they get the $8B promised for Paxlovid - we can only wonder what their contracts say. A $45B base business is plausible but only if the revenue they give up to all the hands in the drug channel cookie jar stabilizes. The rope-a-dope they have been giving the street on Comirnaty uptake (24% - really!) accompanied by a large dollop of "uncertainty" argues for some walking back in October. Let's see where they go.

More in the replay here

Timestamps below.

0:00 - 1:33 - Introduction

1:34 - 8:45 - Inflation and consumption

8:45 - 26:22 Comirnaty: guidance, uptake assumptions and model for US and EU; commercialization snags; Google trends and public health counter detailing

26:22 - 33:09 Paxlovid: guidance, assumptions and model; inventory; relationship to tests positive and receding threats

33:09 - 42:23 Base business: revenue diversion acceleration, guidance and model; role of AMGN settlement with FTC

42:23-46:00 Guidance v. street v Hedgeye: some reconciliation is in order

Let me know if you have any questions.

Emily Evans
Managing Director – Health Policy



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