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In the clip above from this morning's edition of "The Macro Show," Hedgeye CEO Keith McCullough responds to a subscriber asking for help repositioning their portfolio and dealing with a loss.

"A major mistake that people do is that they make a mistake, look back and say 'I shouldn't have done that', but then they still stay with it," says McCullough. "The only way to get rid of a mistake in investing is to get out of it."